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READ FIRST AND WELCOME TO THE INFOWARS FRONTLINE

Re: READ FIRST AND WELCOME TO THE INFOWARS FRONTLINE

#htottpfm datapool FRAUD
ARREST #BEJINGBIDEN EVEN AN ACTOR NO REAL BIDEN DEMAND DNA TESTING. THIS IS THE OVERTAKE OF THE USA BY A TERROR ORG AGAINST US INTERESTS. MEANS FULL DESTRUCTION MERKEL STYLE POLITICS BILDERBERGER NWO.

THE NWO #CORONASPRAYERS A LONG TERM PLANNED SATANIC ACT OF THE MASON BILDERBERGER TALMUD-ORDER ILLUMINATI NAZIJEW SOCIOPATHS TERROR GROUP FOR DESTRUCTION OF TRUMP AS MASTER MIND ENEMY OF GLOBALIZATION (JEWISH WORLDOVERTAKE NWO AND SLAVERY OF MANKIND MEANS GENOCIDE THEY STARTED NOW BY MRNA VACCINATIONS)

VOTER FRAUD FOR NWO OVERTAKE OF THE USA BY HACKING IN BIDEN DOUBLE

ALL THESE ARE SATANIC CULT TO PISS ON WESTERN CHRISTIAN NATIONS VALUES.

ARMYGUILLOTINE FOR THESE RESPONSIBLE. KILL THEIR SOCIOPATHS SOULS.



.
.
#htottpfm datapool ELECTION FRAUD 2020

About to bring it to an end and Biden double to Gitmo

Demand DNA TESTING

End the dem lib terror on the USA
FULL DESTRUCTION MERKEL BILDERBERGER NAZIJEW MAFIA STYLE

https://gab.com/Analyst2021/posts/106733977634261177

https://wego.social/post/4638361

https://rumble.com/vi1or5-rsbn-live.html



If George Sorro got ARRESTED 10 years ago for his ELECTIONS FRAUD IMPACT high criminal activities We wont have all this shit today!!! #htottpfm datapool FRAUD #htotttgsca datapool SORRO CRIMINAL ACTIVITIES


https://wego.social/post/4639652





THIS IS A FACEBOOK FACTCHECK FREE ZONE
OUT OF THE FACT OF FACEBOOK AS A HIDDEN MILITARY SPY OPERATION FOR NWO AND NO FASCIST HITLERMAKERS LIKE FACEBOOK FACTCHECK OPERATORS WORKING AS CRIMINALS AGAINST THE LAW AND FREE INFORMATION ACT BUT NEW WORLD ORDER INTERESTS ARE GETTING IN CONTACT WITH MY ACCOUNT UNDER MY NAME WHICH IS UNDER THE PROTECTION OF THE AMERICAN CONGRESS

http://infofacebook.org







GEORGE SORROS RIGGED VOTING MACHINES

http://hightoweroftrump.org/rigged%20vo … hines.html

GEORGE SORRO THE #ENEMYOFSTATE INDEPENDENT NATION USA FOR THE HITLERMAKERS NWO GOYIM OVERTAKE

http://hightoweroftrump.org/about/enemy … index.html

THE NWO OVERTAKE WEAPON IMMIGRATION OVERRUN HOW THEY CREATED ISRAEL WHATFOR HITLER WAS INSTALLED BY GB

http://hightoweroftrump.org/about/enemy … errun.html

http://hitlermakers.international




#htottpfm datapool ELECTION FRAUD

#2ndterm #freetheUSA1776=#freethetheUSA2020=#freetheUSA2021 #antiNWO_ops
#draintheswamp #CATCHTHEMSHREDDTHEM


https://wego.social/post/4074421_kraken … p-htt.html

Kraken HOT! WildKraken VidArchive || https://newtube.app/user/WildKraken WK Backup || https://vid8.poal.co/user/WildKraken
Big Court Win In Arizona | The George Show 1:56:12 || FoxNews Host Asks Dr. Carson if Biden is Legit Pres, Here’s Carson’s Response 2:20 4.24.21 Why is AZ so Importnt? Demons are Screaming! Winning! Pray! - AWK 45:56 || Yellow team scrutinizing ballots closely, curious if they suspect fake ballots? CodeMonkeyZ 1:56 || Journalists Not Allowed - RMadCow 1:36 || AZ Audit - Liberty In Action 0:59 || Kash Patel Resp to Allegations & Reflects on Declass, Exposing Uyghur 6:55 || Never Thought I’d See This Happen - Dan Bongino 58:18 || STREET JUSTICE Dinesh D’Souza Podcast Ep 74 59:25 || Leaked audio principal admitting making white students feel 'less than' 4:34 || Glenn Frey The Heat Is On - ScottyMar10 10: 08 || Opposing Voter ID is Racist | Change My Mind | Steven Crowder 1:20:17 || Language & NWord Warnings - Bush terrorist - Old timer 3:20 Q Video 2:21 General Michael Flynn Speech at The Freedom Conference Tulsa Oklahoma. 27:50 || Russia Russia Russia 1: 09 || I Wear My Face Mask in the Car 4: 01 || Republicans Against Democracy - KarliQ 1:21 || NCSWIC 1:13 Five finger death punch wash it all away - ScottyMar10 5: 01 || Defensive Violence Warning - We need our 2nd Amend so we can eat in peace! @TruthGiver1776 ☠️ 0:36 || FEEL IT!! FEEL THE VICTORY! I can almost taste it - KarliQ 0:31

Open intro study all
THE PLANDEMIC IS A POLITICAL OPERATION ORGANIZED BY THE SAME BEHIND THE FRAUD!!

#htotttp Pelocy, Biden, Obama, Killary #Gitmo + #armyguillotine +all the other NWO crap HIGHCRIME ALERT #htotki
#htotwib EVEN KILLARY STILL FREE!
Epstein ALIVE!!
http://hightoweroftrump.org/about/wrong … biden.html

THE VACCINATION KILLS
THE PFIZER MODERNA BIONTECH MRNA TRANSFER EVERY PERSON INTO MUTANTS EVEN THE EXCREMENTS OF THEM ARE A DANGER!!

SUCH A CRIMINAL ACT NEEDS THE MILITARY
ALL INVOLVED HAVE GET CATCHED AND THE VACCINATION THAT DOESNT HELP ANYWAY JUST KILL PEOPLE HAVE INSTANTLY STOPPED!!

HOW IS THIS POSSIBLE???
ITS A CRIMINAL ACT OF THE HITLERMAKERS
ROYAL HOUSE OF ENGLAND OWNER OF CLUB 300
BILDERBERGER OWNER OF
USA
GERMANY
AUSTRALIA
CANADA.

BILL GATES COUSIN TO QUEEN ELISABETH II
WANTED TO MAKE HER PROUD.
HES INSANE.
ALL HAVE A INSANE OPINION ABOUT MANKIND FOR THEM WE ARE JUST ANTS!
THAT WHY THEY CREATED HITLER GEORGE V SON AND SENDED HIM TO GERMANY SINCE THEN THE GERMANS ARE SLAVES.

THE ANTISEMITISM WAS INSTALLED BY UK
THE HOLOCAUST EVEN INSTALLED BY UK
FOR CREATING OF ISRAEL.

ITS IMPOSSIBLE IN THE TIMES OF FREE INFORMATION AND INTERNET!

NOONE VOTED FOR BIDEN
BECAUSE OF CRIMES AS VP

BECAUSE OF THE MEXICAN GULF OIL SPILL
OBAMA RESPONSIBLE WITH HIM AS VP

BECAUSE OF THE FUKUSHIMA ATTACK ON JAPAN ABOUT 9/11 REMARKS OBAMA RESPONSIBLE WITH HIM AS VP

BECAUSE OF 47 YEARS OF USELESS POLITICAL NONSENSE

BECAUSE HES #DEMENTIAJOE

BECAUSE OF #BENGHASI OBAMA RESPONSIBLE WITH HIM AS VP

BECAUSE OF CRIME SCENE CHINA SCANDAL

BECAUSE OF CRIME SCENE UCRAINE SCANDAL

BECAUSE HIS WHOLE #BIDENCRIMEFAMILY

AND HE IS #PEDOBIDEN PROOFED OUT OF COURTCASE


BIDEN VOTERS ARE A DANGER FOR THE FREE USA AS BIDEN IS A DANGER AND #ENEMYOFSTATE OF THE USA AND FREE WORLD AS MASON BILDERBERGER TALMUD-ORDER ILLUMINATI NAZIJEW MAFIA MUPPET LIKE MERKEL MAE MACRON TRUDEAU

BIDEN VOTERS ARE
POLITICAL NUTS THIN AIR

#htotbid
#htotbidm
#htotbidcs
#htotbidus


Trumptrains history
#DJTthinktank4 2015-2021
http://supporters-desk.com/ Board link: Topic

#NWO_ops CORONA COV ID 19
http://supporters-desk.com/ Board link: Topic

#nwo_ops US ELECTIONS FRAUD
http://supporters-desk.com/ Board link: Topic

#nwo_ops # Benghazi WHAT REALLY HAPPEND IN LIBYA
http://supporters-desk.com/ Board link: Topic

#nwo_ops # FUKUSHIMA WAS ABOUT 9/11
http://supporters-desk.com/ Board link: Topic

#nwo_ops # MEXICANGULFOILSPILLERS
http://supporters-desk.com/ Board link: Topic

#nwo_ops RIGGED US DEM LIBS BILDERBERGER MUPPETS
http://supporters-desk.com/ Board link: Topic

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Edited by: SD_ECBS BEN - Aug-11-21 23:16:47

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Re: READ FIRST AND WELCOME TO THE INFOWARS FRONTLINE

Great the oscars are now down to zero
As jewish NWO racism
Trumpsters platform for nuts.


Folks the Oscars were always about filming acting movies dreams

Not freaks gay nuts Adrenochrome
Hell

Thank you

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Re: READ FIRST AND WELCOME TO THE INFOWARS FRONTLINE

#htot datapool Hightoweroftrump
Even on Googles

NOONE IS INTERESTED IN THE OSCARS

AS EVIL NWO PROPAGANDA MACHINE FOR GLOBALIZATION
FULL OF RASCISM AND OTHER BASHING NONSENSE

https://twitter.com/MorningBrew/status/ … .social%2F

BUH BYE HOLLYWOOD
WHERE THE PEOPLE WERE NICE AND LIVING SO GOOD

FORMALLY DREAMLAND OF MOVIES STORYTELLING AND LOVE WITHOUT
THIS NWO BULLSHIT

http://uafe.net
HOLLYWOOD ILLUMINATI SHREDD

.

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Re: READ FIRST AND WELCOME TO THE INFOWARS FRONTLINE

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Re: READ FIRST AND WELCOME TO THE INFOWARS FRONTLINE

#fuckblock #facebook

NWO NAZIS YOU ARE SUPPORTING THE GENOCIDE ON WORLDPOPULATION SO YOU GET HIT BE THE NUREMBERG CODE AS FASCISTS SUPPORT GROUND BY SURPRESSING INFORMATION ABOUT !"!!!!!


FUCK YOU
FUCK THE NWO
FUCK FACEBOOK


http://infofacebook.org


FREE INFORMATION IS A HUMAN RIGHT #htotfia datapool #freeinformationact even on fucking illuminati Googles

Edited by: SD_ECBS BEN - Apr-29-21 13:58:30

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Re: READ FIRST AND WELCOME TO THE INFOWARS FRONTLINE

#htot datapool Hightoweroftrump
#htotfia datapool #freeinformationact is a human right


https://www.bitchute.com/channel/ziJRmzzdvEEN


Tonns of new stuff online
The lost Videos


#Copyandpastewillhealtheworld

http://copyandpastewillhealtheworld.com

Presented by the

http://EARTH-COLONIES-BROADCASTING-SERVICE.NET



THE CREATORS OF WUHAN VIRUS


Dr. Baric at UNC, Chapel Hill
Search list via DuckDuckGo searchengine


The HHS in 2014 sent a letter to the University of North Carolina at Chapel Hill where they announced they were going to defund the program. Dr. Ralph S. Baric was identified in the letter. After the work stopped in the US, the Chinese moved forward with the project and ran research and development in Wuhan at the Wuhan Virology Center.


https://www.thegatewaypundit.com/2021/0 … -2019-know




THE TLDR OF WHY COVID-19 VIRUS (SARS-CoV2, the Virus)

                * is > 99.99 MAN-MADE. *

The Must Know:
    The Virus has a "crown" of S (spike) Proteins.
    The S-Protein has sections S1 and S2.
    S1 is the "grabber." (of ACE2)
    S2 is the "key." (fuses w cell)


https://wego.social/post/4303125


The grabber part latches onto the ACE-2 receptor on target cell membrane's surface.

(For simplicity) The Virus then fuses w the target cell when  the body's own enzymes "furin" and "TMPRSS-2" cut the S-protein at specific locations (and it changes shape).



The narrative being fed by WHO and many experts is:

1- A bat coronavirus specie that goes by the name RaTG13 is 96% identical to the Virus (SARS-CoV2).

Dr. Li-Meng Yan thinks RaTG13 is a fraud (doesn't exist):

https://twitter.com/DrLiMengYAN1




2- A pangolin coronavirus has a nearly identical S-protein to the Virus.

But, the pangolins that died of the coronavirus in question came from Malaysia, ~1,000 miles away.

This virus and RaTG13 are distant cousins -> highly unlikely to meet in the same host (for gene mixing).



There is a peculiar sequence of amino acids in SARS-CoV2 that is missing from RaTG13, pangolin virus.

    "PRRA" shown in the top row of pic.

Note that "nCoV-2019" is another name for SARS-CoV2.

Source: (biorxiv[dot]org)

https://www.biorxiv.org/content/10.1101 … 207v1.full


"PRRA"=proline arginine arginine alanine.

The enzyme "furin" mentioned earlier specifically cleaves the sequence "RRAR" (leave out P, add R on right)

This "cleavage site" exists in many coronaviruses, BUT

* NOT at this "ideal spot,"
* And NOT in this "clade" (family)


US researchers have been cutting and pasting viral genomes like Lego blocks since around 2003.

The pioneer in this field is Dr. Ralph Baric at U of N Carolina.

The linked article provides footnotes to scientific articles.

https://www.organicconsumers.org/blog/c … n-cleavage


In 2015, the Wuhan Institute of Virology brought 2 bat coronaviruses from a cave in Yunnan (2013 mine outbreak), Rs3367 and SHC014, to the lab of Dr. Baric at UNC, Chapel Hill, and "collaborated" in making yet another chimeric virus. Question is, what did WIV take back to China?



Bill Gates is a billionaire who showed psychopathic traits in some old interviews..

He donated ~$1 billion to National Natural Science Foundation, CN in 2015, the same year WIV scientists brought the two bat coronaviruses to UNC.


The acknowledgements in the PubMed article makes it plain for anyone to see. Fauci did not fund #Wuhan, but Dr. Baric at UNC Chapel Hill, who got an exception to the GOF research halt announced in 2014, and funneled funds thru EcoHealth.

The CN side was Bill Gates.


https://wego.social/post/4303001_bill-g … rview.html




.

Edited by: SD_ECBS BEN - May-16-21 20:06:42

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Re: READ FIRST AND WELCOME TO THE INFOWARS FRONTLINE

HIGHTOWEROFTRUMP THINKTANK
May 07, 2021 18:31:40 - Translate
Open Intro read all, study all, see complete Video to be seen!!!!
SEE HOW THE NWO HIGHCRIMINALS MISLEADED PRESIDENT TRUMP ABOUT WARP SPEED VACCINATION

WE ARE AT WAR. THE NWO WANT TO ERASE THE THINKING PART OF MANKIND THE ENEMY OF THE NWO LIKE TRUMP IF FINDING OUT THE CORONA MRNA VACCINATION IS A KILLER

#htotcoron #htottt5g
https://www.brighteon.com/71d36e3e-4c4a … 355737b8be

#htotcoron datapool WUHAN VIRUS even tonns of Information on Googles.

At the moment I only work on the CORONA VACCINATIONS WARNING CONCERNING mRNA

Worldwide dont vaxx its a killer. Vaccinations are generally dangerous since 3 decades full of shit Aluminium, Mercury and the reason for Cancer, Parkinson and Alzheimer as profittool of private companies so this is Business of the state not private companies who obviously make really evil things with it like a holocaust style genocide. All hidden lose their life and fertility and end as AIDS/HIV wreck.






WUHAN VIRUS INTRO 1
http://supporters-desk.com/ Board link: Topic

WUHAN VIRUS INTRO 2
http://supporters-desk.com/ Board link: Topic

WUHAN VIRUS ANALYSIS 2021
http://supporters-desk.com/ Board link: Topic

WUHAN VIRUS ANALYSIS 2020
http://supporters-desk.com/ Board link: Topic


GERMAN NEWSFEED 2021
http://supporters-desk.com/ Board link: Topic





Read more
Brighteon
Human 2.0 - Physician warns about new vaccine technology - Interview with Dr. Carrie Madej (MIRRORED) What are the implications of a rushed vaccine for the coronavirus? Dr. Carrie Madej, DO, an oste

Write a comment and press enter
Send
McFarlane profile picture
McFarlane   
May 07, 2021 14:26:39 - Translate
Keep an eye on Dr. Reiner Fullmich... This SHOULD BE in the news... If your local news is not touching this subject, they are harming every citizen they are meant to inform...

A team of over 1,000 lawyers and over 10,000 medical experts lead by Dr. Reiner Fullmich have begun legal proceedings over the CDC, WHO, the Davos Group for crimes against humanity. Fullmich and his team present the faulty PCR test and the order for doctors to label any comorbidity death as a Covid death as fraud. The PCR test was never designed to detect pathogens and is 100% faulty at 35 cycles. All the PCR tests issued by the CDC are rated at 37 to 45 cycles. The CDC admits that any test over 28 cycles are not admissible for any positive reliable result. This alone invalidates over 90% of the alleged covid infections tracked by the use of this faulty test.
In addition to the flawed tests and fraudulent death certificates, the “experimental” vaccine itself is in violation of Article 32 of the Geneva Convention. Under Article 32 of the 1949 Geneva Convention IV, “mutilation and medical or scientific experiments not necessitated by the medical treatment of a protected person” are prohibited. According to Article 147, conducting biological experiments on protected persons is a grave breach of the Convention.
The “experimental” vaccine is in violation of all 10 of the Nuremburg Codes which carry the death penalty for those who seek to violate these International Laws.






#htotcoron
People are pissed but proof of a experimental electro magnetic nanorobotic injection.

Dont take this shit folks you all die within 3 years

https://www.bitchute.com/video/ejJGBw2an5P7



CONCERNING THE CORONA COV ID 19 PLANDEMIC SATANIC NWO BILDERBERGER ECOFORUM ACT THE VACCINATED WILL BECOME THE MONSTERS IN THIS CASE OF A HIGH RATE NATURALLY MUTATING VIRUS EVEN IN THE OUTSIDE MILLIONS OF VACCINATED BECOME MUTANT VIRUSES GENERATORS UNTIL THEY DIE ON THE MRNA TECHNOLOGY ANYWAY

https://www.bitchute.com/video/XvoQEM5vVbdE/

Edited by: SD_ECBS BEN - May-20-21 07:46:04

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Re: READ FIRST AND WELCOME TO THE INFOWARS FRONTLINE

SADLY THE NWO BILDERBERGER ECOFORUM FUCKERS WORK ON THEIR
WORLDWAR Z POPULATION AND MANKIOND IS THAT STUPID THAT THEY LET THEM DOING SINCE 15 MONTHS

mRNA VAXX KILLING BUT
100 % NONSENSE IN THE WHO VACCINATIONS PROGRAM!!!!
NO POSITIVE EFFECT

ITS JUST ABOUT KILLING PEOPLE
CREATING CHAOS
WORLDOVERTAKE OF THE NWO NAZIJEWS

https://wego.social/post/4329701_htotco … y-nwo.html


THE VAXXED ARE THE DANGER NOW HIGH RATE MUTANT VIRUS EVEN IN NATURE THE NWO FUCKER NOW WANT TO GREATER THE VIRUS POPULATION BY INMFECTED MUTANTS MANKIND SO THGE NWO PROFIT

1. mRNA KILLING IN MONTHS 100% PROOF (insane) supporters-desk.com
2. GROWING OF THE CORONA VIRUS PROBLEM (insane)
3. DIGITAL SIGNING OF ALL VAXXED WITHOUT PERMISSION (insane)
4. USE THEM AS BITCOIN GENERATORS MICROSOFT OS mRNA (insane)

https://www.bitchute.com/video/XvoQEM5vVbdE

STUDY ALL
http://supporters-desk.com/ Board link: Forum



MASTER
.
#htotcoron datapool WUHAN VIRUS
#htottt5G datapool 5G mobil Phone technology
#nwo_ops datapool MASON BILDERBERGER TALMUD-ORDER NAZIJEW ILLUMINATI MAFIA BRAINDAMAGED SOCIOPATHS

FUCKING IMAGINE THAT ASTRA-ZENECA VACCINATED HAVE BLUETOOTH AUTOCONNECTED SHOW ON EVERY DEVICE ON EARTH

NOT THAT YOU JUST GET KILLED FROM THE MRNA IN IT UP TO THEN

- YOU ARE LOCATED
- YOUR DIGITAL ENVIRONMENT CAN GET SWITCH OFFLINE IF YOU ARE A ENEMY OF THE NWO
...=Credit cards
...=Mobile phones
...=Computers
...=NEW Electronic cars
.
THE BILDERBERGER ECOFORUM FUCKERS WORK ON THEIR WORLDWAR Z ON MANKIND
.
.
SEE THIS VIDEO

https://www.bitchute.com/video/D0QgDp8IkoS0

https://www.bitchute.com/video/7bTF8u84elmt

ZERO POSITIVE EFFECT OF THE CORONA VACCINATIONS PROGRAM
ITS NOT WORKING BUT KILLS, CREATES A MASSIVE MUTANT MANKIND WAVE PRPDUCING FOR VIRUS MUTANTS IN THEIR BODIES
THEY HAVE TO GET SEPARATED AND KILLED THATS WHY FEMA CAMPS ARE FOR

https://wego.social/post/4334170

#htotcoron datapool WUHAN VIRUS even tonns of Information on Googles. #covidsideeffects #AntiBodyEnhancement, #COVID19, #covidvaccinesideeffects, #Covideffectonplacenta, #stopmedicaldescriminationorg, #americasfrontalinedoctors #experimental #htottt5g #cov_ID19 #covid19UK  #CORONA #COVID19france #COVID19 #COVID #COVID19NL #COVID2019italia #COVID19USA #COVID19WORLD #NWO_OPS #EVILPHARAOEMPIRE
#Covid_19PH #CoronaVirusUpdates #coronapocalypse #CoronaIreland #coronavirus #Covid_19 #COVIDー19 #COVID19de #CoronaVirusUpdates  #Corona #CoronaOutbreak #Korona #koronowirus

ITS NOT ABOUT HEALTH BUT DAMAGING AND ENSLAVERY OF MANKIND A NWO OPERATION #NWO_OPS

WOW MINUTE 11:50 VACCINATED ARE SO DANGEROUS TO PREGNANT...

STOP THE COVID VAXX MRNA INSANITY

https://www.brighteon.com/2aaed9bc-aa22 … 0f2059983a
IT DOES NOT WORK ONLY KILLING!!!!







SEE ALL

http://supporters-desk.com/ Board link: Forum


SEE ALL

https://www.bitchute.com/channel/ziJRmzzdvEEN





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Re: READ FIRST AND WELCOME TO THE INFOWARS FRONTLINE

https://rightsfreedoms.wordpress.com/20 … cinations/


57 Top Scientists and Doctors: Stop All Covid Vaccinations

9 mai 2021

Peter A. McCullough, MD, MPH
Image: Peter A. McCullough, MD, MPH is one of the experts. Press photo
A group of 57 leading scientists, doctors, and policy experts has released a report calling in to question the safety and efficacy of the current Covid-19 vaccines and are now calling for an immediate end to all vaccine programs.

This article was previously published on En-volve.com (feel free to share this report)

There are two certainties regarding the global distribution of Covid-19 vaccines. The first is that governments and the vast majority of the mainstream media are pushing with all their might to get these experimental drugs into as many people as possible. The second is that those who are willing to face the scorn that comes with asking serious questions about vaccines are critical players in our ongoing effort to spread the truth.

You can read an advanced copy of this manuscript in preprint below. It has been prepared by nearly five dozen highly respected doctors, scientists, and public policy experts from across the globe to be urgently sent to world leaders as well as all who are associated with the production and distribution of the various Covid-19 vaccines in circulation today.

There are still far too many unanswered questions regarding the Covid-19 vaccines’ safety, efficacy, and necessity. This study is a bombshell that should be heard by everyone, regardless of their views on vaccines. There aren’t nearly enough citizens who are asking questions. Most people simply follow the orders of world governments, as if they have earned our complete trust. They haven’t done so. This manuscript is a step forward in terms of accountability and the free flow of information on this crucial subject. Please take the time to read it and share it widely.

SARS-CoV-2 mass vaccination: Urgent questions on vaccine safety that demand answers from international health agencies, regulatory authorities, governments and vaccine developers

Roxana Bruno1, Peter McCullough2, Teresa Forcades i Vila3, Alexandra Henrion-Caude4, Teresa García-Gasca5, Galina P. Zaitzeva6, Sally Priester7, María J. Martínez Albarracín8, Alejandro Sousa-Escandon9, Fernando López Mirones10, Bartomeu Payeras Cifre11, Almudena Zaragoza Velilla10, Leopoldo M. Borini1, Mario Mas1, Ramiro Salazar1, Edgardo Schinder1, Eduardo A Yahbes1, Marcela Witt1, Mariana Salmeron1, Patricia Fernández1, Miriam M. Marchesini1, Alberto J. Kajihara1, Marisol V. de la Riva1, Patricia J. Chimeno1, Paola A. Grellet1, Matelda Lisdero1, Pamela Mas1, Abelardo J. Gatica Baudo12, Elisabeth Retamoza12, Oscar Botta13, Chinda C. Brandolino13, Javier Sciuto14, Mario Cabrera Avivar14, Mauricio Castillo15, Patricio Villarroel15, Emilia P. Poblete Rojas15, Bárbara Aguayo15, Dan I. Macías Flores15, Jose V. Rossell16, Julio C. Sarmiento17, Victor Andrade-Sotomayor17, Wilfredo R. Stokes Baltazar18, Virna Cedeño Escobar19, Ulises Arrúa20, Atilio Farina del Río21, Tatiana Campos Esquivel22, Patricia Callisperis23, María Eugenia Barrientos24, Karina Acevedo-Whitehouse5,*

1Epidemiólogos Argentinos Metadisciplinarios. República Argentina.
2Baylor University Medical Center. Dallas, Texas, USA.
3Monestir de Sant Benet de Montserrat, Montserrat, Spain
4INSERM U781 Hôpital Necker-Enfants Malades, Université Paris Descartes-Sorbonne Cité, Institut Imagine, Paris, France.
5School of Natural Sciences. Autonomous University of Querétaro, Querétaro, Mexico.
6Retired Professor of Medical Immunology. Universidad de Guadalajara, Jalisco, Mexico.
7Médicos por la Verdad Puerto Rico. Ashford Medical Center. San Juan, Puerto Rico.
8Retired Professor of Clinical Diagnostic Processes. University of Murcia, Murcia, Spain
9Urologist Hospital Comarcal de Monforte, University of Santiago de Compostela, Spain.
10Biólogos por la Verdad, Spain.
11Retired Biologist. University of Barcelona. Specialized in Microbiology. Barcelona, Spain.
12Center for Integrative Medicine MICAEL (Medicina Integrativa Centro Antroposófico Educando en Libertad). Mendoza, República Argentina.
13Médicos por la Verdad Argentina. República Argentina. ´
14Médicos por la Verdad Uruguay. República Oriental del Uruguay.
15Médicos por la Libertad Chile. República de Chile.
16Physician, orthopedic specialist. República de Chile.
17Médicos por la Verdad Perú. República del Perú.
18Médicos por la Verdad Guatemala. República de Guatemala.
19Concepto Azul S.A. Ecuador.
20Médicos por la Verdad Brasil. Brasil.
21Médicos por la Verdad Paraguay.
22Médicos por la Costa Rica.
23Médicos por la Verdad Bolivia.
24Médicos por la Verdad El Salvador.
* Correspondence: Karina Acevedo-Whitehouse, karina.acevedo.whitehouse@uaq.mx

Abstract

Since the start of the COVID-19 outbreak, the race for testing new platforms designed to confer immunity against SARS-CoV-2, has been rampant and unprecedented, leading to emergency authorization of various vaccines. Despite progress on early multidrug therapy for COVID-19 patients, the current mandate is to immunize the world population as quickly as possible. The lack of thorough testing in animals prior to clinical trials, and authorization based on safety data generated during trials that lasted less than 3.5 months, raise questions regarding the safety of these vaccines. The recently identified role of SARS-CoV-2 glycoprotein Spike for inducing endothelial damage characteristic of COVID-19, even in absence of infection, is extremely relevant given that most of the authorized vaccines induce the production of Spike glycoprotein in the recipients. Given the high rate of occurrence of adverse effects, and the wide range of types of adverse effects that have been reported to date, as well as the potential for vaccine-driven disease enhancement, Th2-immunopathology, autoimmunity, and immune evasion, there is a need for a better understanding of the benefits and risks of mass vaccination, particularly in the groups that were excluded in the clinical trials. Despite calls for caution, the risks of SARS-CoV-2 vaccination have been minimized or ignored by health organizations and government authorities. We appeal to the need for a pluralistic dialogue in the context of health policies, emphasizing critical questions that require urgent answers if we wish to avoid a global erosion of public confidence in science and public health.

Introduction

Since COVID-19 was declared a pandemic in March 2020, over 150 million cases and 3 million deaths have been reported worldwide. Despite progress on early ambulatory, multidrug-therapy for high-risk patients, resulting in 85% reductions in COVID-19 hospitalization and death [1], the current paradigm for control is mass-vaccination. While we recognize the effort involved in development, production and emergency authorization of SARS-CoV-2 vaccines, we are concerned that risks have been minimized or ignored by health organizations and government authorities, despite calls for caution [2-8].

Vaccines for other coronaviruses have never been approved for humans, and data generated in the development of coronavirus vaccines designed to elicit neutralizing antibodies show that they may worsen COVID-19 disease via antibody-dependent enhancement (ADE) and Th2 immunopathology, regardless of the vaccine platform and delivery method [9-11]. Vaccine-driven disease enhancement in animals vaccinated against SARS-CoV and MERS-CoV is known to occur following viral challenge, and has been attributed to immune complexes and Fc-mediated viral capture by macrophages, which augment T-cell activation and inflammation [11-13].

In March 2020, vaccine immunologists and coronavirus experts assessed SARS-CoV-2 vaccine risks based on SARS-CoV-vaccine trials in animal models. The expert group concluded that ADE and immunopathology were a real concern, but stated that their risk was insufficient to delay clinical trials, although continued monitoring would be necessary [14]. While there is no clear evidence of the occurrence of ADE and vaccine-related immunopathology in volunteers immunized with SARS-CoV-2 vaccines [15], safety trials to date have not specifically addressed these serious adverse effects (SAE). Given that the follow-up of volunteers did not exceed 2-3.5 months after the second dose [16-19], it is unlikely such SAE would have been observed. Despite92 errors in reporting, it cannot be ignored that even accounting for the number of vaccines administered, according to the US Vaccine Adverse Effect Reporting System (VAERS), the number of deaths per million vaccine doses administered has increased more than 10-fold. We believe there is an urgent need for open scientific dialogue on vaccine safety in the context of large-scale immunization. In this paper, we describe some of the risks of mass vaccination in the context of phase 3 trial exclusion criteria and discuss the SAE reported in national and regional adverse effect registration systems. We highlight unanswered questions and draw attention to the need for a more cautious approach to mass vaccination.

SARS-CoV-2 phase 3 trial exclusion criteria

With few exceptions, SARS-CoV-2 vaccine trials excluded the elderly [16-19], making it impossible to identify the occurrence of post-vaccination eosinophilia and enhanced inflammation in elderly people. Studies of SARS-CoV vaccines showed that immunized elderly mice were at particularly high risk of life-threatening Th2 immunopathology [9,20]. Despite this evidence and the extremely limited data on safety and efficacy of SARS-CoV-2 vaccines in the elderly, mass-vaccination campaigns have focused on this age group from the start. Most trials also excluded pregnant and lactating volunteers, as well as those with chronic and serious conditions such as tuberculosis, hepatitis C, autoimmunity, coagulopathies, cancer, and immune suppression [16-29], although these recipients are now being offered the vaccine under the premise of safety.

Another criterion for exclusion from nearly all trials was prior exposure to SARS-CoV-2. This is unfortunate as it denied the opportunity of obtaining extremely relevant information concerning post-vaccination ADE in people that already have anti-SARS-Cov-2 antibodies. To the best of our knowledge, ADE is not being monitored systematically for any age or medical condition group currently being administered the vaccine. Moreover, despite a substantial proportion of the population already having antibodies [21], tests to determine SARS-CoV-2-antibody status prior to administration of the vaccine are not conducted routinely.

Will serious adverse effects from the SARS-CoV-2 vaccines go unnoticed?

COVID-19 encompasses a wide clinical spectrum, ranging from very mild to severe pulmonary pathology and fatal multi-organ disease with inflammatory, cardiovascular, and blood coagulation dysregulation [22-24]. In this sense, cases of vaccine-related ADE or immunopathology would be clinically-indistinguishable from severe COVID-19 [25]. Furthermore, even in the absence of SARS-CoV-2 virus, Spike glycoprotein alone causes endothelial damage and hypertension in vitro and in vivo in Syrian hamsters by down-regulating angiotensin-converting enzyme 2 (ACE2) and impairing mitochondrial function [26]. Although these findings need to be confirmed in humans, the implications of this finding are staggering, as all vaccines authorized for emergency use are based on the delivery or induction of Spike glycoprotein synthesis. In the case of mRNA vaccines and adenovirus-vectorized vaccines, not a single study has examined the duration of Spike production in humans following vaccination. Under the cautionary principle, it is parsimonious to consider vaccine-induced Spike synthesis could cause clinical signs of severe COVID-19, and erroneously be counted as new cases of SARS-CoV-2 infections. If so, the true adverse effects of the current global vaccination strategy may never be recognized unless studies specifically examine this question. There is already non-causal evidence of temporary or sustained increases138 in COVID-19 deaths following vaccination in some countries (Fig. 1) and in light of Spike’s pathogenicity, these deaths must be studied in depth to determine whether they are related to vaccination.

Unanticipated adverse reactions to SARS-CoV-2 vaccines

Another critical issue to consider given the global scale of SARS-CoV-2 vaccination is autoimmunity. SARS-CoV-2 has numerous immunogenic proteins, and all but one of its immunogenic epitopes have similarities to human proteins [27]. These may act as a source of antigens, leading to autoimmunity [28]. While it is true that the same effects could be observed during natural infection with SARS-CoV-2, vaccination is intended for most of the world population, while it is estimated that only 10% of the world population has been infected by SARS-CoV-2, according to Dr. Michael Ryan, head of emergencies at the World Health Organization. We have been unable to find evidence that any of the currently authorized vaccines screened and excluded homologous immunogenic epitopes to avoid potential autoimmunity due to pathogenic priming.

Some adverse reactions, including blood-clotting disorders, have already been reported in healthy and young vaccinated people. These cases led to the suspension or cancellation of the use of adenoviral vectorized ChAdOx1-nCov-19 and Janssen vaccinesin some countries. It has now been proposed that vaccination with ChAdOx1-nCov-19 can result in immune thrombotic thrombocytopenia (VITT) mediated by platelet-activating antibodies against Platelet factor-4, which clinically mimics autoimmune heparin-induced thrombocytopenia [29]. Unfortunately, the risk was overlooked when authorizing these vaccines, although adenovirus-induced thrombocytopenia has been known for more than a decade, and has been a consistent event with adenoviral vectors [30]. The risk of VITT would presumably be higher in those already at risk of blood clots, including women who use oral contraceptives [31], making it imperative for clinicians to advise their patients accordingly.

At the population level, there could also be vaccine-related impacts. SARS-CoV-2 is a fast-evolving RNA virus that has so far produced more than 40,000 variants [32,33] some of which affect the antigenic domain of Spike glycoprotein [34,35]. Given the high mutation rates, vaccine-induced synthesis of high levels of anti-SARS-CoV-2-Spike antibodies could theoretically lead to suboptimal responses against subsequent infections by other variants in vaccinated individuals [36], a phenomenon known as “original antigenic sin” [37] or antigenic priming [38]. It is unknown to what extent mutations that affect SARS-CoV-2 antigenicity will become fixed during viral evolution [39], but vaccines could plausibly act as selective forces driving variants with higher infectivity or transmissibility. Considering the high similarity between known SARS-CoV-2 variants, this scenario is unlikely [32,34] but if future variants were to differ more in key epitopes, the global vaccination strategy might have helped shape an even more dangerous virus. This risk has recently been brought to the attention of the WHO as an open letter [40].

Discussion

The risks outlined here are a major obstacle to continuing global SARS-CoV-2 vaccination. Evidence on the safety of all SARS-CoV-2 vaccines is needed before exposing more people to the184 risk of these experiments, since releasing a candidate vaccine without time to fully understand the resulting impact on health could lead to an exacerbation of the current global crisis [41]. Risk-stratification of vaccine recipients is essential. According to the UK government, people below 60 years of age have an extremely low risk of dying from COVID-191 187 . However, according to Eudravigillance, most of the serious adverse effects following SARS-CoV-2 vaccination occur in people aged 18-64. Of particular concern is the planned vaccination schedule for children aged 6 years and older in the United States and the UK. Dr. Anthony Fauci recently anticipated that teenagers across the country will be vaccinated in the autumn and younger children in early 2022, and the UK is awaiting trial results to commence vaccination of 11 million children under 18. There is a lack of scientific justification for subjecting healthy children to experimental vaccines, given that the Centers for Disease Control and Prevention estimates that they have a 99.997% survival rate if infected with SARS-CoV-2. Not only is COVID-19 irrelevant as a threat to this age group, but there is no reliable evidence to support vaccine efficacy or effectiveness in this population or to rule out harmful side effects of these experimental vaccines. In this sense, when physicians advise patients on the elective administration of COVID-19 vaccination, there is a great need to better understand the benefits and risk of administration, particularly in understudied groups.

In conclusion, in the context of the rushed emergency-use-authorization of SARS-CoV-2 vaccines, and the current gaps in our understanding of their safety, the following questions must be raised:

Is it known whether cross-reactive antibodies from previous coronavirus infections or vaccine206 induced antibodies may influence the risk of unintended pathogenesis following vaccination with COVID-19?
Has the specific risk of ADE, immunopathology, autoimmunity, and serious adverse reactions been clearly disclosed to vaccine recipients to meet the medical ethics standard of patient understanding for informed consent? If not, what are the reasons, and how could it be implemented?
What is the rationale for administering the vaccine to every individual when the risk of dying from COVID-19 is not equal across age groups and clinical conditions and when the phase 3 trials excluded the elderly, children and frequent specific conditions?
What are the legal rights of patients if they are harmed by a SARS-CoV-2 vaccine? Who will cover the costs of medical treatment? If claims were to be settled with public money, has the public been made aware that the vaccine manufacturers have been granted immunity, and their responsibility to compensate those harmed by the vaccine has been transferred to the tax-payers?
In the context of these concerns, we propose halting mass-vaccination and opening an urgent pluralistic, critical, and scientifically-based dialogue on SARS-CoV-2 vaccination among scientists, medical doctors, international health agencies, regulatory authorities, governments, and vaccine developers. This is the only way to bridge the current gap between scientific evidence and public health policy regarding the SARS-CoV-2 vaccines. We are convinced that humanity deserves a deeper understanding of the risks than what is currently touted as the official position. An open scientific dialogue is urgent and indispensable to avoid erosion of public confidence in science and public health and to ensure that the WHO and national health authorities protect the interests of humanity during the current pandemic. Returning public health policy to evidence-based medicine, relying on a careful evaluation of the relevant scientific research, is urgent. It is imperative to follow the science.

1 https://www.gov.uk/government/publicati … and-report

Conflict of Interest Statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

References

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